School of Biomedical Sciences
The Chinese University of Hong Kong 香港中文大學


The Cancer Biology & Experimental Therapeutics (CBET) thematic research program conducts research in understanding the basic mechanisms of tumor initiation and progression, with a long-term goal in translating this knowledge into effective cancer treatment. The Cancer Biology branch of CBET focuses on identifying and studying the molecular defects associated with cancers of the prostate, liver, pancreas, breast, nasopharynx, head and neck, and epidermoid carcinoma. Research activities include studying defects in signaling molecules that control cancer cell behaviors, global genomic, transcriptomic and epigenomic profiling of cancer cells, elucidating the role of inflammation in tumor development, and the development of bioinformatics tools for “omics” analysis. The Experimental Therapeutics branch focuses on translational cancer pharmacogenomics, preclinical studies of the anti-tumor effects of biologics and Chinese Herbal extracts, and developing new therapeutics for chemoprevention and the alleviation of chemotherapy-induced side effects including nausea and emesis. The strategic long-term vision of the CBET aims to promote synergism between basic and translational research with the goal of developing innovative molecular-based therapies for human cancers.

Educational Mission

The major education goal of CBET is to train the next generation of cancer researchers. Members of the CBET are actively involved in training graduate students enrolled in the MPhil-PhD program in Biomedical Sciences. Apart from laboratory-based research, students are taught the latest advances in cancer research through didactic lectures, technical workshops, and journal clubs. The CBET is also participating in teaching undergraduate elective courses for students enrolled in the BSc in Biomedical Sciences. These courses will provide students with an introduction to the etiology, classification, and treatment of human cancers.

Enquiry for research matters, please contact us at This email address is being protected from spambots. You need JavaScript enabled to view it.

Name Contact No. Research Interests
Prof CHAN Leung Franky 3943 6841 Prostate cancer, cancer stem cells,
nuclear receptors and mediated
signalling pathways, epithelial-
mesenchymal transition, immunotherapy
Prof CHAN Man Lok Andrew 3943 3771 Oncogenes, tumor suppressors,
cell signaling
Prof CHEN Yangchao 3943 1100 Pancreatic cancer, liver cancer,
long non-coding RNA, circular RNA,
EZH2, anti-cancer agent
Prof CHENG Sze Lok Alfred (Chief) 3943 9842 Cancer epigenetics,  tumor immunology/
immunotherapy, enhancer regulation
Prof LIN Ge 3943 6824 PK, ADMET, herb-induced liver injury,
herb-drug interaction, safety and
activity of herbal medicines
Prof RUDD John Anthony 3943 6789 Nausea, vomiting, emesis, anti-emetic,
myoelectric activity, peptide, diabetes,
Parkinson, electrogastrogram
Prof SO Hon Cheong (Deputy Chief) 3943 9255 Bioinformatics, statistics; psychiatry, 
machine learning, risk prediction, 
genomics, genome-wide association 
study, sequencing, high dimensional
data analysis
Prof TONG Man Carol 3943 3115 Cancer metabolism, tumor microenvironment,
therapy resistance, novel combination therapy,
cancer stemness
Prof TSUI Kwok Wing Stephen 3943 6381 Genomics and bioinformatics study of
allergic diseases and cancer
Prof ZHOU Jingying 3943 1350 Epigenetic regulations in tumor
associated immune cells
Name Contact No. Research Interests
Prof CAO Qin Cara 3943 6805 Bioinformatics, Computational biology,
Machine learning, Gene regulatory networks,
Multi-omics data, 3D genome structures
Dr LONG Xiaohang 3943 9843 Genomic and epigenomic alterations in liver cancer,
Molecular mechanism of immunotherapy resistance,
Therapeutic targets for liver cancer
Name Contact No.
Prof CHAN L. Stephen 3505 2166
Prof CHAN Sze Wa Stella 3653 6661
Prof CHAN Tak Cheung Anthony 3505 2119
Prof LAI Bo San Paul 3505 1496
Prof LAN Hui Yao 3763 6077
Prof LO Kwok Wai 3505 2178
Prof NG Chi Fai 3505 2625
Prof NG Wai-Lung Billy 3943 0671
Prof. TO Kin Wah Kenneth 3943 8017
Prof WONG Nathalie 3505 1128
Prof WU Ka Kei William 3505 3147
Prof YU Jun 3763 6099


CBET cell line protein RNA (version 1.0)

Cancer metabolism, tumor microenvironment, therapy resistance, novel combination therapy, cancer stemness