The Cancer Biology & Experimental Therapeutics (CBET) thematic research program conducts research in understanding the basic mechanisms of tumor initiation and progression, with a long-term goal in translating this knowledge into effective cancer treatment. The Cancer Biology branch of CBET focuses on identifying and studying the molecular defects associated with cancers of the prostate, liver, pancreas, breast, nasopharynx, head and neck, and epidermoid carcinoma. Research activities include studying defects in signaling molecules that control cancer cell behaviors, global genomic, transcriptomic and epigenomic profiling of cancer cells, elucidating the role of inflammation in tumor development, and the development of bioinformatics tools for “omics” analysis. The Experimental Therapeutics branch focuses on translational cancer pharmacogenomics, preclinical studies of the anti-tumor effects of biologics and Chinese Herbal extracts, and developing new therapeutics for chemoprevention and the alleviation of chemotherapy-induced side effects including nausea and emesis. The strategic long-term vision of the CBET aims to promote synergism between basic and translational research with the goal of developing innovative molecular-based therapies for human cancers.

Educational Mission

The major education goal of CBET is to train the next generation of cancer researchers. Members of the CBET are actively involved in training graduate students enrolled in the MPhil-PhD program in Biomedical Sciences. Apart from laboratory-based research, students are taught the latest advances in cancer research through didactic lectures, technical workshops, and journal clubs. The CBET is also participating in teaching undergraduate elective courses for students enrolled in the BSc in Biomedical Sciences. These courses will provide students with an introduction to the etiology, classification, and treatment of human cancers.

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Name Contact No. Research Interests
Prof CHAN Leung Franky 3943 6841 Prostate cancer, cancer stem cells, nuclear
receptors and mediated signalling pathways,
epithelial-mesenchymal transition,
Prof CHAN Man Lok Andrew (Chief) 3943 3771 Oncogenes, tumor suppressors,
cell signaling
Prof CHEN Yangchao 3943 1100  
Prof CHENG Sze Lok Alfred (Deputy Chief) 3943 9842 Cancer epigenetics,  tumor immunology/
immunotherapy, enhancer regulation
Prof CHEUNG Wing Tai 3943 6104 Antibody engineering, Tumour immunology,
GPCR biology, Lipid signalling
Prof FUNG Kwok Pui 3943 6873  
Prof LAU Hang Yung Alaster 3943 6846 Allergy, cancer, inflammation, mast cells,
pharmacology, osteoporosis
Prof LIN Ge 3943 6824 PK, ADMET, herb-induced liver injury,
herb-drug interaction, safety and
activity of herbal medicines
Prof LUI Wai Yan Vivian 3943 5388 Precision medicine, Genomics, Proteomics,
Immune-genomic interactions, Head and
Neck Cancers
Prof Rudd John Anthony 3943 6789  
Prof SO Hon Cheong 3943 9255  
Prof TSUI Kwok Wing Stephen 3943 6381 Genomics and bioinformatics study of
allergic diseases and cancer
Prof ZHOU Jingying 3943 9843

Epigenetic regulations in tumor associated
immune cells

Name Contact No.
Prof CHAN Sze Wa Stella 36536661
Prof CHAN Tak Cheung Anthony 26322119
Prof KUMTA Shekhar Madhukar 26321279
Prof LAI Bo San Paul 26321496
Prof LAN Hui Yao 37636077
Prof LO Kwok Wai 26322178
Prof NG Chi Fai 26322625
Prof NG Siu Man Simon 26321495
Prof TO Kin Wah Kenneth 39438017
Prof WONG Nathalie 26321128
Prof WU Ka Kei William 26323147
Prof YU Jun 37636099


CBET cell line protein RNA (version 1.0)