School of Biomedical Sciences
生物醫學學院
The Chinese University of Hong Kong 香港中文大學

Developmental and Regenerative Biology

Development and diseases

  • Embryonic and fetal development and reproductive tract environment in health and diseases including prematurity, Hirschprung’s disease, neural crest defects, cardiac diseases and diabetic pregnancies.
  • Development and regeneration of peripheral nerves, craniofacial development, deafness and eye diseases.
  • Genetic and molecular basis of skeletal disorders
  • Wnt/Planar cell polarity (Wnt/PCP) signaling in development and disease.

 

Stem cells and tissue engineering

  • Regulatory mechanisms of stem cell differentiation (microRNA, ion channels, long non-coding RNAs) and stem cell therapy in tissue regeneration.
  • Generation, biological, genetic and genomic characterization, and clinical application of induced pluripotent stem (iPS) cells, embryonic stem cells and mesenchymal stem cells (MSC).
  • Application of iPS cells as disease models including neurological diseases and cancers and as tools for drug discoveries.
  • Stem cell biology and cell-based therapies
  • Stem cell-based tissue engineering, biomaterials, artificial intelligence, deep learning, label-free cell tracking, musculoskeletal regeneration, orthopaedic research, small molecules and 3D microphysiological tissue models for regenerative medicine.
  • Molecular regulation of stem cells in aging and age-related diseases

 

Developmental genomics, genetics and epigenetics

  • Genetics and genomics of organogenesis, and functional genomics, epigenetics and cell biology of the reproductive epithelia, developing germ cells, embryonic gonads and reproductive tumors.
  • Inherited and congenital diseases and personalized medicine.
  • Molecular mechanisms of acute kidney injury and chronic kidney disease.
  • CRISPR and gene-editing technologies for gene and cell therapies to treat human diseases.

 

Name Contact No. Research Interests
Prof BLOCKI Anna Maria (Deputy Co-Chief) 3943 9797 Tissue Engineering, regenerative medicine,
biomaterials, stem cells, cell-based therapy,
hydrogel, extracellular matrix
Prof CHAN Hon Fai Vivas 3943 3032 Tissue engineering, liver regeneration, stem cell,
microfluidics, biomaterial, biomechanics
Prof. CHAN Pui Barbara 3943 0509 Tissue engineering and regenerative medicine, enabling technologies, biomaterials, complex organoid and tumoroids, cell niche engineering, mechanoregulation
Prof CHAN Wai Yee 3943 1383 Genetic diseases, germ cells, differentiation, tumor,
microRNA, epigenetics 
Prof CHAN Wood Yee (Co-Chief) 3943 6895 Stem cell therapy, development of enteric nervous
system, neural crest stem cells, stem cell migration
and differentiation, congenital gut disorders,
cell transplantation, mouse embryonicdevelopment,
Hirschsprung’s disease, irritable bowel syndrome,
neural crest cell induction
Prof CHEUNG Hoi Hung Albert 3943 9796 Stem cell differentiation and aging 
Prof DALTON Stephen (Co-Chief) 3943 0537 Pluripotent and adult stem cells, Cardiac development,
Brown and beige adipocytes,
Therapeutic development for type 2 diabetes
Prof FENG Bo 3943 1455 Genome editing, Stem cells, Gene and cell therapy,
Inherited hematopoietic and metabolic disorders
Prof FOK Kin Lam Ellis 3943 9986 Infertility, assisted reproduction technologies,
male contraceptive, sperm functions, spermatogenesis,
germline stem cell biology, germ cell transplantation,
testis microenvironment, cancer/testis genes
Prof GAO Bo (Deputy Co-Chief) 3943 6801 Skeletal Biology, Skeletal Disorders, Wnt/PCP signaling in development and disease
Prof GU Shen Linda 3943 5747 Molecular mechanisms of deleterious genetic
alterations in inheritable human diseases
Prof JIANG Xiaohua 3943 1229 Stem cell epigenetics, stem cell therapy,
stem cell microenvironment, aging
Prof JIANG Yangzi 3943 5153 Tissue Degeneration and Tissue Regeneration:
Osteoarthritis
Prof KO Wing Hung 3943 6781 Epithelial transport, Ca2+/cAMP signaling,
purinergic receptors, Heme oxygenase,
carbon monoxide, airway inflammation,
fluorescence imaging
Prof SHAM Mai Har 3943 0415 Molecular mechanisms of mammalian development
and human congenital disorders,
transcriptional regulation, functional genomics,
craniofacial, inner ear and sensory neural
development, neural crest and placode,
stem cells and regeneration
Prof TUAN Rocky S. 3943 5204  
Prof WAN Chao 3943 4494 Bone, cartilage, degeneration, regeneration,
stem cells, small molecules, tissue engineering
Prof WANG Dan Michelle 3943 4497 Bone tendon tissue engineering, extracellular
matrix, stem cells, immunomodulation
Prof XIA Yin 3943 4480 Kidney physiology, injury and repair,
Male reproductive biology,
Metabolic signaling pathways in the liver
Prof ZHAO Hui 3943 1344 Embryonic development, tumorigenesis of
neuroblastoma, tissue regeneration and therapy
Name Contact No. Research Interests
Prof WANG Wuming 3943 0570 ESC pluripotency, cardiac development and disease,
genome editing
Prof CHAN Chung Ngor Juliana 3505 3138
Dr CHAN Leung Kwok Clement ---
Prof CHAN Wan Yi Renee 3513 3175
Prof CHENG Chun Yiu Jack 3505 2729
Prof CHOY Kwong Wai Richard 3505 3099
Prof ITO Takahiro ---
Prof LEUNG Ting Fan 3505 2860 / 3505 2850
Prof LI Chi Kong 3505 1019
Prof LI Gang 3505 3592 / 3763 6153
Prof LI Zhong Alan 3943 5906
Prof POON Wai Sang 3505 2624
Prof TANG Leung Sang Nelson 3505 2320
Prof WANG Huating 3763 6047
Prof YUNG Shu-hang Patrick 3505 2728

 

 

 

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