School of Biomedical Sciences
生物醫學學院
The Chinese University of Hong Kong 香港中文大學


CHAN Sun OnProfessor

B.Sc., M.Phil, D.Phil.

Telephone: 39436898

Email:   This email address is being protected from spambots. You need JavaScript enabled to view it.

Address:

  307A, Lo Kwee-Seong Integrated Biomedical Sciences Building, Area 39, CUHK

 

  1. Roles of axon growth regulating molecules on axon guidance in the optic chiasm and spinal cord
  2. Anti-inflammatory and anti-oxidative mechanisms in ocular diseases
  1. Chan SO and Guillery RW (1993), Developmental changes produced in the retinofugal pathways of rats and ferrets by early monocular enucleations: The effects of age and the differences between normal and albino animals, Journal of Neuroscience 13: 5277-5293
  2. Chan SO, Baker GE and Guillery RW (1993), Differential action of the albino mutation on two components of the rats uncrossed retinofugal pathways, Journal of Comparative Neurology 336: 362-377
  3. Chan SO and Guillery RW (1994), Changes of fiber order in the optic nerve and tract of rat embryos, Journal of Comparative Neurology 344: 20-32
  4. Chan SO, Wong KF, Chung KY and Yung WH (1998), Changes in morphology and behaviour of retinal growth cones before and after crossing the midline of the mouse chiasm – a confocal microscopy study, European Journal of Neuroscience 10: 2511-2522
  5. Chan SO, Chung KY and Taylor JSH (1999), The effects of early prenatal monocular enucleations on the routing of uncrossed retinofugal axons and the cellular environment at the chiasm of mouse embryos, European Journal of Neurosciences 11: 3225-3235
  6. Chan SO and Chung KY (1999), Changes in axon arrangement in the retinofugal pathway of mouse embryos – A confocal microscopy study using single- and double-dye label, Journal of Comparative Neurology 406: 251-262
  7. Chung KY, Shum DKY and Chan SO (2000), Expression of chondroitin sulfate proteoglycans in the chiasm of mouse embryos, Journal of Comparative Neurology 417: 153-163
  8. Chung KY, Taylor JSH, Shum DKY and Chan SO (2000), Axon routing at the optic chiasm after enzymatic removal of chondroitin sulfate in mouse embryos, Development 127: 2673-2683
  9. Leung KM, Taylor JSH and Chan SO (2003), Enzymatic removal of chondroitin sulfates abolishes the age-related axon order in the optic tract of mouse embryos, European Journal of Neuroscience 17: 1755-1767
  10. Lin L and Chan SO (2003), Perturbation of CD44 function affects chiasmatic routing of retinal axons in brain slice preparations of the mouse retinofugal pathway, European Journal of Neuroscience 17: 2299-2312
  11. Chung KY, Leung KM, Lin CC, Tam KC, Hao YL, Taylor JSH and Chan SO (2004), Regionally specific expression of L1 and sialylated NCAM in the retinofugal pathway of mouse embryos, Journal of Comparative Neurology 471: 482-498
  12. Lin L, Wang J, Chan CK, Chan SO (2007), Effects of exogenous hyaluronan on midline crossing and axon divergence in the optic chiasm of mouse embryos, European Journal of Neuroscience 26: 1-11
  13. Wang J, Chan CK, Taylor JSH and Chan SO (2008), Localization of Nogo and its receptor in the optic pathway of mouse embryos, Journal of Neuroscience Research 86: 1721-1733
  14. Wang J, Chan CK, Taylor JSH and Chan SO (2008), The growth inhibitory protein, Nogo, is involved in midline routing of axons in the mouse optic chiasm, Journal of Neuroscience Research 86: 2581-2590
  15. Wang J, Wang LQ, Zhao H and Chan SO (2010), Localization of an axon growth inhibitory molecule Nogo and its receptor in the spinal cord of mouse embryos, Brain Research 1306: 8-17
  16. Poon MW, Tsang WH, Waye MMY and Chan SO (2011), Distribution of Kiaa0319-like immunoreactivity in the adult mouse brain - a novel protein encoded by the putative dyslexia susceptibility gene KIAA0319-like, Histology and Histopathology 26: 953-963
  17. Yang Y, Ng TK, Ye C, Yip YWY, Law KS, Chan SO and Pang CP (2014), Assessing sodium iodate induced outer retinal changes in rats using confocal scanning laser ophthalmoscopy and optical coherence tomography Investigative Ophthalmology and Visual Science 55: 1696-1705
  18. Wang LQ, Lam JSY, Zhao H, Wang J and Chan SO (2014), Localization of protein kinase C isoforms in the optic pathway of mouse embryos and their role in axon routing in the optic chiasm, Brain Research 1575: 22-32
  19. Qin YJ, Chu KO, Yip YWY, Li WY, Yang YP, Chan KP, Ren JL, Chan SO and Pang CP (2014), Green tea extract treatment alleviates ocular inflammation in a rat model of endotoxin-induced uveitis, PLoS ONE 9: e103995, pp. 1-12
  20. Qin YJ, Chan SO, Chong KKL, Li BFL, Ng TK, Yip YWY, Chen H, Zhang M, Block NL, Cheung HS, Schally AV and Pang CP (2014), Antagonist of GH-releasing hormone receptors alleviates experimental ocular inflammation, Proceedings of National Academy of Science USA 111: 18303-18308