School of Biomedical Sciences
生物醫學學院
The Chinese University of Hong Kong 香港中文大學

TSUI Kwok Wing Stephen

Professor

BSc, DipEd, PhD

Telephone:  39436381

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Website:  http://ihome.sbs.cuhk.edu.hk/StephenTsui

Address:

 524A, Lo Kwee-Seong Integrated Biomedical Sciences Building, Area 39, CUHK

 

  1. The functional roles of FHL2 family proteins in liver cancer
  2. The mutation-drug matching for cancer patients
  3. The roles of dust mites in allergic diseases
  4. Changes in microbiota in human diseases
  5. Multi-omic analysis in diabetes
  1. Yang, K.Y., Chen, Y., Ng, P.K.S., Zhou, W.J., Chen, J.Y., Mao, B.Y. and Tsui, S.K.W. (2016). Transcriptome analysis of different developmental stages of amphioxus reveals dynamic changes of distinct classes of genes during development. Sci, Rep., 6, 23195.
  2. Zhang, Y., Li, S.K., Yang, K.Y., Liu, M.H., Lee, N., Tang, X., Wang, H., Liu, L., Chen, Z., Zhang, C.Y., Wang, J.H., Tsui, S.K.W. (2015). Whole genome methylation array reveals the down-regulation of IGFBP6 and SATB2 by HIV-1. Sci. Rep., 5, 10806.
  3. Liu, M.H., Yang, B.R., Cheung, W.F., Yang, K.Y., Zhou, H.F., Kwok, J.S.L., Liu, G.C., Li, X.F., Zhong, S., Lee, S.M.Y. and Tsui, S.K.W. (2014), Transcriptome analysis of leaves, roots and flowers of Panax notoginseng identifies genes involved in ginsenoside and alkaloid biosynthesis, BMC Genomics, in press.
  4. Chan, T.F., Ji, K.M., Yim, A.K.Y., Liu, X.Y., Zhou, J.W., Li, R.Q., Yang, K.Y., Li, J., Li, M., Law, P.T.W., Wu, Y.L., Cai, Z.L., Qin, H., Bao, Y., Leung, R.K.K., Ng, P.K.S., Zou, J., Zhong, X.J., Ran, P.X., Zhong, N.S., Liu, Z.G., and Tsui, S.K.W. (2015). The draft genome, transcriptome and microbiome of Dermatophagoides farinae reveal a broad spectrum of dust mite allergens. J. Allergy Clin. Immunol., 135, 539-548.
  5. Lou, S., Lee, H.M., Qin, H., Li, J.W., Gao, Z., Liu, X., Chan, L.L., Lam, V., So, W.Y., Wang, Y., Lok, S., Wang, J., Ma, R., Tsui, S.K.W., Chan, J., Chan, T.F. and Yip, K.Y. (2014). Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation. Genome Biol., 15, 408.
  6. Leung, T.F., Ko, F.W.S., Sy, H.Y., Tsui, S.K.W. and Wong, G.W.K. (2014). Differences in asthma genetics between Chinese and other populations. J. Allergy Clin. Immunol., 133, 42-48.
  7. Leung, R.K.K., Zhou, J.W., Guan, W., Li, S.K., Yang, Z.F., and Tsui, S.K.W. (2013). Modulation of potential respiratory pathogens by pH1N1 viral infection. Clin. Microbiol. Infect., 19, 930-935.
  8. Chan, T.M., Leung, K.S., Lee, K.H., Wong, M.H., Lau, C.K., and Tsui, S.K.W. (2012). Subtypes of associated Protein-DNA (TF-TFBS) patterns. Nucleic. Acid Res., 40, 9392-9403.
  9. Li, S.K., Leung, R.K.K., Guo, H.X., Wei, J.F., Wang, J.H., Kwong, K.T., Lee, S.S., Zhang, C. and Tsui, S.K.W. (2012). Detection and identification of plasma bacterial and viral elements in HIV/AIDS patients in comparison to healthy adults. Clin. Microbiol. Infect., 18, 1126-1133.
  10. Ng, C.F., Ng, P.K.S., Lui, V.W.Y., Li, J., Chan, J.Y.W., Fung, K.P., Ng, Y.K., Lai, P.B.S. and Tsui, S.KW. (2011). FHL2 exhibits anti-proliferative and anti-apoptotic activity in liver cancer cells. Cancer Letters, 304, 97-106.
  11. Chan, T.M., Wong, K.C., Lee, K.H., Wong, M.H., Lau, C.K., Tsui, S.K.W. and  Leung, K.S. (2011). Discovering approximate-associated sequence patterns for protein-DNA interactions. Bioinformatics, 27, 471-478.
  12. Leung, K.S., Wong, K.C., Chan, T.M., Wong, M.H., Lee, K.H., Lau, C.K. and Tsui, S.K.W. (2010). Discovering protein-DNA binding sequence patterns using association rule mining, Nucleic. Acids. Res.,. 38, 6324-6337.
  13. Sung, J.J.Y., Tsui, S.K.W., Tse, C.H., Ng, Y.E.T., Leung, K.S., Lee, K.H., Mok, T.S.K., Bartholomeusz, A., Au, T.C.C., Tsoi, K.K.F., Locarnini, S., Chan, H.L.Y. (2008). Genotype-specific genomic markers associated with primary hepatoma, based on complete genomic sequencing of hepatitis B virus. J Virol, 82, 3604-3611
  14. Frazer KA, ....Tsui SKW et al. [author 77 out of 262] (2007). A second generation human haplotype map of over 3.1 million SNPs. Nature, 449, 851-861.
  15. Sabeti, P.C., .... Tsui, S.K.W. et al. [author 65 out of 250] (2007). Genome-wide detection and characterization of positive selection in human populations. Nature, 449, 913-918.
  16. The International HapMap Consortium (2005), A haplotype map of the human genome. Nature, 437, 1299-1320
  17. Chim, S.S.C.*, Tsui, S.K.W.* et al. [author 2 out of 17] (2003). Genomic characterization of the SARS-coronavirus of the Amoy Gardens outbreak in Hong Kong. Lancet, 362, 1807-1808 (*co-first authors).
  18. Tsui, S.K.W., Chim, S.S.C., Lo, Y.M.D. and the Chinese University of Hong Kong Molecular SARS Research Group (2003). Coronavirus genomic-sequence variations and the epidemiology of the severe acute respiratory syndrome. N. Engl. J. Med., 349, 187-188.
  19. Hwang, D.M., Dempsey, A.A., Wang, R.X., Rezvani, M., Barrans, J.D., Dai, K.S., Wang, H.Y., Ma, H., Cukerman, E., Liu, Y.Q., Gu, J.R., Zhang, J.H., Tsui, S.K.W. and Waye, M.M.Y., Fung, K.P., Lee, C.Y., Liew, C.C. (1997). A genome-based resource for molecular cardiovascular medicine - Towards a compendium of cardiovascular genes. Circulation, 96, 4146-4203.
  20. Liew, C.C., Hwang, D.M., Fung, Y.W., Laurenssen, C., Cukerman, E., Tsui, S.K.W. and Lee, C.Y. (1994). A catalogue of genes in the cardiovascular system as identified by expressed sequence tags (ESTs). Proc. Natl. Acad. Sci. USA, 91, 10645-10649