It prints 3D scaffolds as substrate for cell culture and organoids. It also seeds cells using the GeSim piezoelectric pipettes. The instrument is also equipped with metal nozzles and cartridges for precise temperature controlled thermoplast printing and high temperature piston extruder for printing plastic granules at >200°C, etc. The platform fits in a biological safety cabinet.
Features:
GUI-based windows software, pre-configured
Intuitive “Scaffold generator” for the easy generation of simple forms and the slicing of CAD data (STL and 3MF files)
3 independent z-drives for cartridges, plus one for a liquid dispenser (piezo) and a z-sensor
Paste printing controlled by compressed air
Choice of cartridge holders, for ambient temperature, or heatable (to > 120°C)
Tip cleaner for wiping off excess material
Z-sensor for the measurement of substrate heights plus tip measuring tool for automatic alignment of dispensers
Piezoelectric GeSIM pipette (heatable/non-heatable, various sub-nanolitre volumes) can aspirate samples from a (heatable) microtitre plate
Piezo dispenser includes bottles, tubing, syringe pump, wash/dry stations, and stroboscope for a functional test
External electronic control unit with embedded computer (“F-Box”), connects to sensor cables, compressed air and system liquid (water)
Adjustable dosage pressure: 100-600 kPa (1-6 bar)
Step width: 2mm in X/Y (belt-driven). 10 um in Z encoder-controlled