There are three foci:

1. Aging and Degeneration
   
   Group members are interested in studying basic mechanisms of cognitive disorders and associated central nervous system diseases including depression, drug abuse, and changes in pain pathways that occur during aging. There is also an interest to look at degenerative changes occurring in the autonomic system and in the gastrointestinal tract.
   
   
2. Development, Injury and Related Diseases
   
   The group has interests in a variety of topics including gene determinates in eye and brain development and pathogenesis, in developmental dyslexia and suicide as well as the role of ribosomal inactivating proteins during morphogenesis. The molecular guidance in the formation of neural pathways in cortex, visual system and spinal cord is also a prominent direction.
   
   
3. Brain Plasticity and Repair Group
   
   Members of the Brain Plasticity and Repair Group have on-going projects include studying the functions of neurotrophic factors in synaptic plasticity, the role of brain iron in neurodegenerative disease and possible therapeutic interventions, the use of the retina model to study repair of central nervous system, and the effect of chronic or intermittent hypoxia on neuronal injury, protection and plasticity. These projects concentrated on the functional adaptation, regeneration and healing processes.
   
   In all three foci, culture studies, imaging, behavioral studies as well as biochemical and other molecular techniques will be employed.

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